RAF Typhoon FGR4s have operated alongside France's air force in a coordinated attack on an underground arms cache in Syria operated by the IS group, according to the British defence ministry.
The facility, located using intelligence, was thought to be housing weapons and explosive materials, the release indicated, and was positioned in mountainous terrain just above Palmyra in central Syria.
"The RAF jets utilized precision-guided Paveway IV munitions to strike a several approach shafts leading to the facility... preliminary assessments are that the objective was successfully hit," the ministry announced.
There was no indication of any civilian casualties in the strike late on Saturday and all the aircraft returned to base without incident, the defence officials confirmed.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
IS - alternatively referred to as Daesh - enforced extremist governance over parts of Syria and Iraq before its territorial defeat in 2019.
"This strike shows the UK's leading role, and commitment to stand shoulder to shoulder with our partners, to stamp out any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," Britain's Defence Chief the minister stated.
British military aircraft have carried out surveillance missions over Syrian airspace to "forestall any attempted resurgence" of Islamic State following its routing at the climactic battle in Baghuz in 2019, the ministry said.
"I must thank all the members of British forces participating in this mission for their professionalism and their valour," Healey commented. "They were part of thousands of British troops stationed over Christmas and New Year. This action, to remove militants who threaten our security, highlights how our armed forces are always on standby, throughout the year, keeping Britain secure at home and influential overseas."
Last December, the United States armed forces carried out what it described as a "massive strike" targeting IS targets in the country, after an assault killed two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations reports IS still has an estimated 5,000 to 7,000 combatants in Iraq and Syria.
